RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-142
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
qRT-PCR;
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-142-3p inhibits high-glucose-induced endothelial-to-mesenchymal transition through targeting TGF-beta1/Smad pathway in primary human aortic endothelial cells
Year
2018
Function
"miR-142-3p also mediated its anti-endothelial-to-mesenchymal transition (EndMT) action by inactivation of TGF-beta/smad pathway, as demonstrated by downregulation of TGF-beta, phospho-smad2 and phospho-smad2."